Abstract: The paper uses the entropy method and the coupling coordination model to calculate the development level and the spatial and temporal pattern characteristics of the new urbanization and the construction industry in all cities in Yunnan Province from 2012 to 2020. And the spatial autocorrelation is explored through the GeoDa software and the grey correlation model. The following conclusions are drawn: 1) From the perspective of time sequence development, the coordination between new urbanization and construction industry shows a gradually increasing trend. The synergistic development effect has been greatly enhanced. Regional differences are gradually narrowing, and presents a balanced development trend. 2) In terms of the spatial pattern, the moderately coordinated relationship between the new urbanization and the construction industry continues to deepen to the central and western Yunnan, the main performance shows the 'central high, southwest low' distribution pattern. 3) From the perspective of spatial autocorrelation, the coordination between new urbanization and construction industry has significant agglomeration characteristics, mainly manifested as high-high agglomeration and lowlow agglomeration, and spatial correlation is obvious. 4) From the perspective of influencing factors, economic driving factors>environmental guiding factors>industrial structure factors>government regulation factors. Different influencing factors show obvious regional differences in the coordinated development of new urbanization and construction industry. Accordingly, the interactive effect between the two should be strengthened to maintain stability and coordinated development, optimize the allocation of resources to ensure reasonable regional development, and narrow regional differences.